TLR-4 andCD14 Polymorphisms in Respiratory Syncytial Virus Associated Disease

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TLR-4 and CD14 Polymorphisms in Respiratory Syncytial Virus Associated Disease

Respiratory syncytial virus (RSV) is the most common viral respiratory pathogen during infancy world wide. It induces innate and adaptive immune response in host cells. The toll like receptor 4 (TLR4)/CD14 complex is particularly important for the initiation of an innate immune response to RSV. Thus we were interested whether an association exists between severe RSV associated diseases and poly...

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Respiratory Syncytial Virus Fusion Protein Promotes TLR-4–Dependent Neutrophil Extracellular Trap Formation by Human Neutrophils

Acute viral bronchiolitis by Respiratory Syncytial Virus (RSV) is the most common respiratory illness in children in the first year of life. RSV bronchiolitis generates large numbers of hospitalizations and an important burden to health systems. Neutrophils and their products are present in the airways of RSV-infected patients who developed increased lung disease. Neutrophil Extracellular Traps...

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Respiratory syncytial virus-associated hospitalizations in Louisiana.

Respiratory syncytial virus (RSV) is the most common cause of bronchiolitis and pneumonia in children under one year of age worldwide. Records indicative of RSV cases were pulled from The Louisiana Inpatient Hospital Discharge Data based on RSV diagnosis codes to describe the burden of RSV infections in Louisiana from 1999 to 2010. Two thousand to three thousand hospitalized RSV cases occurred ...

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Respiratory Syncytial Virus: Pathogenesis and Disease Burden

Although respiratory syncytial virus (RSV) was first described more than 50 years ago, RSV remains a cause of significant disease burden in infants and young children—especially those who are born prematurely or who have certain underlying diagnoses. Lower respiratory tract infections (LRTIs) develop in a significant percentage of patients who become infected with RSV, often resulting in hospit...

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Respiratory illness associated with influenza and respiratory syncytial virus infection.

AIMS To estimate excess morbidity during periods of influenza and respiratory syncytial virus (RSV) activity. METHODS Retrospective analysis of a sentinel practice network database in active and non-active virus periods. MAIN OUTCOME MEASURES clinical diagnoses of new episodes of influenza-like illness (ILI), acute bronchitis, asthma, and otitis media. RESULTS The clinical diagnosis of IL...

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ژورنال

عنوان ژورنال: Disease Markers

سال: 2006

ISSN: 0278-0240,1875-8630

DOI: 10.1155/2006/865890